Sigmund J Degitz: search on Z-Library

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1

In Vitro , Ex Vivo , and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles

Hornung, Michael W., Kosian, Patricia A., Haselman, Jonathan T., Korte, Joseph J., Challis, Katie, Macherla, Chitralekha, Nevalainen, Erica, Degitz, Sigmund J.

Journal:

Toxicological Sciences

Year:

2015

Language:

english

File:

PDF, 521 KB

english, 2015

2

Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

Olker, Jennifer H, Korte, Joseph J, Denny, Jeffrey S, Hartig, Phillip C, Cardon, Mary C, Knutsen, Carsten N, Kent, Paige M, Christensen, Jessica P, Degitz, Sigmund J, Hornung, Michael W

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 716 KB

english, 2018

3

Role of TGF-β in RA-induced cleft palate in CD-1 mice

Degitz, Sigmund J., Morris, Dale, Foley, George L., Francis, B. Magnus

Journal:

Year:

1998

Language:

english

File:

PDF, 414 KB

english, 1998

4

Pathogenesis of methanol-induced craniofacial defects in C57BL/6J mice

Sigmund J. Degitz, Robert M. Zucker, Clinton Y. Kawanishi, Gwen S. Massenburg, John M. Rogers

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

5

Developmental toxicity of methanol: Pathogenesis in CD-1 and C57BL/6J mice exposed in whole embryo culture

Sigmund J. Degitz, John M. Rogers, Robert M. Zucker, E. Sidney Hunter III

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

2004

Language:

english

File:

PDF, 247 KB

english, 2004

6

Methanol exposure during gastrulation causes holoprosencephaly, facial dysgenesis, and cervical vertebral malformations in C57BL/6J mice

John M. Rogers, Kimberly C. Brannen, Brenda D. Barbee, Robert M. Zucker, Sigmund J. Degitz

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2004

Language:

english

File:

PDF, 351 KB

english, 2004

7

Maternal and developmental toxicity of polychlorinated diphenyl ethers (PCDEs) in Swiss-Webster mice and Sprague-Dawley rats

Kimberly Rosiak, Mei-Hui Li, Sigmund J Degitz, Dale W Skalla, Ih Chu, B.Magnus Francis

Journal:

Year:

1997

Language:

english

File:

PDF, 258 KB

english, 1997

8

Ambient Solar UV Radiation Causes Mortality in Larvae of Three Species of Rana Under Controlled Exposure Conditions

Joseph E. Tietge, Stephen A. Diamond, Gerald T. Ankley, David L. DeFoe, Gary W. Holcombe, Kathleen M. Jensen, Sigmund J. Degitz, Gregory E. Elonen, Edward Hammer

Journal:

Photochemistry and Photobiology

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

9

Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology

Joseph E. Tietge, Gary W. Holcombe, Kevin M. Flynn, Patricia A. Kosian, Joseph J. Korte, Leroy E. Anderson, Douglas C. Wolf, Sigmund J. Degitz

Journal:

Environmental Toxicology and Chemistry

Year:

2005

Language:

english

File:

PDF, 129 KB

english, 2005

10

Reproductive maturation of the tropical clawed frog: Xenopus tropicalis

Allen W. Olmstead, Joseph J. Korte, Kacie K. Woodis, Blake A. Bennett, Shannon Ostazeski, Sigmund J. Degitz

Journal:

General and Comparative Endocrinology

Year:

2009

Language:

english

File:

PDF, 258 KB

english, 2009

11

Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis

Kristin A. Connors, Joseph J. Korte, Grant W. Anderson, Sigmund J. Degitz

Journal:

General and Comparative Endocrinology

Year:

2010

Language:

english

File:

PDF, 446 KB

english, 2010

12

Thyroid-stimulating hormone (TSH): Measurement of intracellular, secreted, and circulating hormone in Xenopus laevis and Xenopus tropicalis

Joseph J. Korte, Robin M. Sternberg, Jose A. Serrano, Kara R. Thoemke, Scott M. Moen, Kathryn E. Lillegard, Michael W. Hornung, Joseph E. Tietge, Sigmund J. Degitz

Journal:

General and Comparative Endocrinology

Year:

2011

Language:

english

File:

PDF, 452 KB

english, 2011

13

Control of pituitary thyroid-stimulating hormone synthesis and secretion by thyroid hormones during Xenopus metamorphosis

Robin M. Sternberg, Kara R. Thoemke, Joseph J. Korte, Scott M. Moen, Jessica M. Olson, Lisa Korte, Joseph E. Tietge, Sigmund J. Degitz Jr.

Journal:

General and Comparative Endocrinology

Year:

2011

Language:

english

File:

PDF, 677 KB

english, 2011

14

Evaluation of gene expression endpoints in the context of a Xenopus laevis metamorphosis-based bioassay to detect thyroid hormone disruptors

Fang Zhang, Sigmund J. Degitz, Gary W. Holcombe, Patricia A. Kosian, Joseph Tietge, Nik Veldhoen, Caren C. Helbing

Journal:

Aquatic Toxicology

Year:

2006

Language:

english

File:

PDF, 411 KB

english, 2006

15

Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay: Part 2. Effects on the tail and hindlimb

Caren C. Helbing, Lan Ji, Carmen M. Bailey, Nik Veldhoen, Fang Zhang, Gary W. Holcombe, Patricia A. Kosian, Joseph Tietge, Joseph J. Korte, Sigmund J. Degitz

Journal:

Aquatic Toxicology

Year:

2007

Language:

english

File:

PDF, 291 KB

english, 2007

16

Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor

Allen W. Olmstead, Patricia A. Kosian, Joseph J. Korte, Gary W. Holcombe, Kacie K. Woodis, Sigmund J. Degitz

Journal:

Aquatic Toxicology

Year:

2009

Language:

english

File:

PDF, 613 KB

english, 2009

17

Genotyping sex in the amphibian, Xenopus (Silurana) tropicalis, for endocrine disruptor bioassays

Allen W. Olmstead, Annelie Lindberg-Livingston, Sigmund J. Degitz

Journal:

Aquatic Toxicology

Year:

2010

Language:

english

File:

PDF, 501 KB

english, 2010

18

Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis

Joseph E. Tietge, Brian C. Butterworth, Jonathan T. Haselman, Gary W. Holcombe, Michael W. Hornung, Joseph J. Korte, Patricia A. Kosian, Marilyn Wolfe, Sigmund J. Degitz

Journal:

Aquatic Toxicology

Year:

2010

Language:

english

File:

PDF, 401 KB

english, 2010

19

Effects of 4-tert-octylphenol on Xenopus tropicalis in a long term exposure

Karen L. Porter, Allen W. Olmstead, David M. Kumsher, William E. Dennis, Robert L. Sprando, Gary W. Holcombe, Joseph J. Korte, Annelie Lindberg-Livingston, Sigmund J. Degitz

Journal:

Aquatic Toxicology

Year:

2011

Language:

english

File:

PDF, 810 KB

english, 2011

20

In vivo assessment and potential diagnosis of xenobiotics that perturb the thyroid pathway: Proteomic analysis of Xenopus laevis brain tissue following exposure to model T4 inhibitors

Jose Serrano, LeeAnn Higgins, Bruce A. Witthuhn, Lorraine B. Anderson, Todd Markowski, Gary W. Holcombe, Patricia A. Kosian, Joseph J. Korte, Joseph E. Tietge, Sigmund J. Degitz

Journal:

Comparative Biochemistry and Physiology Part D: Genomics and Proteomics

Year:

2010

Language:

english

File:

PDF, 805 KB

english, 2010

21

Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin β subunit mRNAs to support endocrine disruptor research

Daniel L. Villeneuve, Ann L. Miracle, Kathleen M. Jensen, Sigmund J. Degitz, Michael D. Kahl, Joseph J. Korte, Katie J. Greene, Lindsey S. Blake, Ann L. Linnum, Gerald T. Ankley

Journal:

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

Year:

2007

Language:

english

File:

PDF, 922 KB

english, 2007

22

Developmental toxicity of methoprene and several degradation products in Xenopus laevis

Sigmund J. Degitz, Elizabeth J. Durhan, Joseph E. Tietge, Patricia A. Kosian, Gary W. Holcombe, Gerald T. Ankley

Journal:

Aquatic Toxicology

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

23

The Hypothalamic-Pituitary-Thyroid (HPT) Axis in Frogs and Its Role in Frog Development and Reproduction

Fort, Douglas J., Degitz, Sigmund, Tietge, Joseph, Touart, Leslie W.

Journal:

Critical Reviews in Toxicology

Year:

2007

Language:

english

File:

PDF, 471 KB

english, 2007

24

Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole

Tietge, Joseph E., Degitz, Sigmund J., Haselman, Jonathan T., Butterworth, Brian C., Korte, Joseph J., Kosian, Patricia A., Lindberg-Livingston, Annelie J., Burgess, Emily M., Blackshear, Pamela E., H

Journal:

Aquatic Toxicology

Year:

2013

Language:

english

File:

PDF, 779 KB

english, 2013

25

Toxicogenomics in Regulatory Ecotoxicology

Ankley, Gerald T., Daston, George P., Degitz, Sigmund J., Denslow, Nancy D., Hoke, Robert A., Kennedy, Sean W., Miracle, Ann L., Perkins, Edward J., Snape, Jason, Tillitt, Donald E., Tyler, Charles R.

Journal:

Environmental Science & Technology

Year:

2006

Language:

english

File:

PDF, 408 KB

english, 2006

26

Global gene expression during early differentiation of Xenopus (Silurana) tropicalis gonad tissues

Haselman, Jonathan T., Olmstead, Allen W., Degitz, Sigmund J.

Journal:

General and Comparative Endocrinology

Year:

2014

Language:

english

File:

PDF, 1.69 MB

english, 2014

27

A Method for the Determination of Genetic Sex in the Fathead Minnow, Pimephales promelas, To Support Testing of Endocrine-Active Chemicals

Olmstead, Allen W., Villeneuve, Daniel L., Ankley, Gerald T., Cavallin, Jenna E., Lindberg-Livingston, Annelie, Wehmas, Leah C., Degitz, Sigmund J.

Journal:

Environmental Science & Technology

Year:

2011

Language:

english

File:

PDF, 1.95 MB

english, 2011

28

Effects of laboratory ultraviolet radiation and natural sunlight on survival and development of Rana pipiens

Ankley, Gerald T, Tietge, Joseph E, Holcombe, Gary W, DeFoe, David L, Diamond, Stephen A, Jensen, Kathleen M, Degitz, Sigmund J

Journal:

Canadian Journal of Zoology

Year:

2000

File:

PDF, 3.37 MB

2000

29

Coexistence of Y, W, and Z sex chromosomes in Xenopus tropicalis

Roco, Álvaro S., Olmstead, Allen W., Degitz, Sigmund J., Amano, Tosikazu, Zimmerman, Lyle B., Bullejos, Mónica

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

30

Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow

Nelson, Krysta R., Schroeder, Anthony L., Ankley, Gerald T., Blackwell, Brett R., Blanksma, Chad, Degitz, Sigmund J., Flynn, Kevin M., Jensen, Kathleen M., Johnson, Rodney D., Kahl, Michael D., Knapen

Journal:

Aquatic Toxicology

Year:

2016

Language:

english

File:

PDF, 1.12 MB

english, 2016

31

Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4- tert -octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile

Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Iguchi, Taisen, Johnson, Rodney D., Degitz, Sigmund J.

Journal:

Journal of Applied Toxicology

Year:

2016

Language:

english

File:

PDF, 328 KB

english, 2016

32

Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile

Haselman, Jonathan T., Sakurai, Maki, Watanabe, Naoko, Goto, Yasushi, Onishi, Yuta, Ito, Yuki, Onoda, Yu, Kosian, Patricia A., Korte, Joseph J., Johnson, Rodney D., Iguchi, Taisen, Degitz, Sigmund J.

Journal:

Journal of Applied Toxicology

Year:

2016

Language:

english

File:

PDF, 520 KB

english, 2016

33

Neurodevelopment and Thyroid Hormone Synthesis Inhibition in The Rat: Quantitative Understanding Within The Adverse Outcome Pathway Framework

Hassan, Iman, El-Masri, Hisham, Kosian, Patricia A., Ford, Jermaine, Degitz, Sigmund J., Gilbert, Mary E.

Journal:

Toxicological Sciences

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

34

Ambient Solar UV Radiation Causes Mortality in Larvae of Three Species of Rana Under Controlled Exposure Conditions†¶

Tietge, Joseph E., Diamond, Stephen A., Ankley, Gerald T., DeFoe, David L., Holcombe, Gary W., Jensen, Kathleen M., Degitz, Sigmund J., Elonen, Gregory E., Hammer, Edward

Journal:

Photochemistry and Photobiology

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

35

Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis : manifestations of antiandrogenic and other modes of toxicity

Haselman, Jonathan T., Kosian, Patricia A., Korte, Joseph J., Olmstead, Allen W., Degitz, Sigmund J.

Journal:

Aquatic Toxicology

Year:

2018

Language:

english

File:

PDF, 845 KB

english, 2018

36

Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

Hornung, Michael W, Korte, Joseph J, Olker, Jennifer H, Denny, Jeffrey S, Knutsen, Carsten, Hartig, Phillip C, Cardon, Mary C, Degitz, Sigmund J

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 595 KB

english, 2018

37

Evaluating iodide recycling inhibition as a novel molecular initiating event for thyroid axis disruption in amphibians

Olker, Jennifer H, Haselman, Jonathan T, Kosian, Patricia A, Donnay, Kelby G, Korte, Joseph J, Blanksma, Chad, Hornung, Michael W, Degitz, Sigmund J

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

38

Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results

LaLone, Carlie, Villeneuve, Daniel L., Doering, Jon A, Blackwell, Brett R, Transue, Thomas R, Simmons, Cody W, Swintek, Joe, Degitz, Sigmund, Williams, Antony J, Ankley, Gerald T.

Journal:

Environmental Science & Technology

Year:

2018

Language:

english

File:

PDF, 777 KB

english, 2018

39

Targeted pathway-based in vivo testing using thyroperoxidase inhibition to evaluate plasma thyroxine as a surrogate metric of metamorphic success in model amphibian Xenopus laevis

Haselman, Jonathan T, Olker, Jennifer H, Kosian, Patricia A, Korte, Joseph J, Swintek, Joseph A, Denny, Jeffrey S, Nichols, John W, Tietge, Joseph E, Hornung, Michael W, Degitz, Sigmund J

Journal:

Toxicological Sciences

Year:

2020

Language:

english

File:

PDF, 2.41 MB

english, 2020

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